In an increasingly globalized world, place matters more than ever. That is certainly the case in Appalachian studies—a field that brings scholars, activists, artists, and citizens together around a region to contest misappropriations of resources and power and combat stereotypes of isolation and intolerance. In Appalachia in Regional Context: Place Matters, the diverse ways in which place is invoked, the person who invokes it, and the reasons behind that invocation all matter greatly. In this collection, scholars and artists are assembled from a variety of disciplines to broaden the conversation. The book begins with chapters challenging conventional representations of Appalachia by exploring theoretically the relationships among regionalism, globalism, activism, and everyday experience. Other chapters examine, for example, foodways, depictions of Appalachian gendered and racialized identity in popular culture, the experiences of rural LGBTQ youth, and the pitfalls and promises of teaching regional studies. Poems by the renowned social critic bell hooks interleave the chapters and add context to reflections on the region. Drawing on cultural anthropology, sociology, geography, media studies, political science, gender and women’s studies, ethnography, social theory, art, music, and literature, this volume furthers the exploration of new perspectives on one of America’s most compelling and misunderstood regions.